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What’s supposed to be the end of a life becomes the beginning of a new one after a failed suicide attempt, albeit with some mental degradation involved that requires relearning the basics. Now known as Bella Baxter (Emma Stone), she becomes the experiment of renowned surgeon Godwin “God” Baxter (Willem Dafoe) who tries to treat her as a mere science project yet can’t distance himself enough emotionally to not serve as her new father figure. He enlists the help of his best medical student Max McCandles (Ramy Youssef) to chart her progress and is eventually designated as her fiancé after witnessing their fondness for one another. Due to the unique and delicate condition of his ward, God employs promiscuous lawyer Duncan Wedderburn (Mark Ruffalo) to draft a special nuptial contract. Out of curiosity, he goes out of his way to get to know the subject of the document and is immediately smitten by her, taking advantage of her naivety and convincing her to run away with him to Portugal, which serves as her first stop in discovering the world and, in effect, rediscovering life itself.